Digital Archive & Compendium
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Quarterly deep-dive compendiums on cellular reprogramming, de novo protein architecture, synthetic biology foundries, and the emerging bioeconomy.
CURRENT EDITION • VOL. 14October 2026124 Pages • Peer-Reviewed Dossiers
The Cellular Reprogramming Frontier
Pulsed Yamanaka Factors, Epigenetic Clocks & The Reversal of Tissue Senescence
Table of Contents Preview (Vol. 14)
COVER DOSSIER
Rewriting the Epigenetic Clock: Partial Reprogramming in Human Tissueby Prof. Shinya Yamanaka • p. 18
The Horvath Methylation Shift: Quantitative Measurement of Biological Reversalby Prof. Steve Horvath • p. 32
SYNTHETIC BIOLOGY & TOOLS
Microbial Chloroplasts: Engineering 18% Higher Photosynthetic Densityby Prof. Frances Arnold • p. 46
Targeted Delivery: The Structural Anatomy of mRNA Lipid Nanoparticlesby Prof. Katalin Karikó • p. 60
BIOBUSINESS & POLICY
The $20B BiTE Bet: Why Big Pharma is Re-Engineering T-Cell Engagersby Carl Zimmer • p. 78
The Ethics of Perfection: Where Does Prevention End and Enhancement Begin?by Prof. Jennifer Doudna • p. 94
LAB PERSPECTIVES
Interview: Prof. David Baker on Generative Biological Foundriesby The BIO Editorial Council • p. 110
The BIO Magazine
Frontiers of Life Sciences & Biotech
VOL. 14 • October 2026
The Cellular Reprogramming Frontier
Pulsed Yamanaka Factors, Epigenetic Clocks & The Reversal of Tissue Senescence
ISSN 2841-9031SPECIAL REPORT
Browsable Archive (2025–2026 Editions)
4 Quarterly Volumes AvailableVOL. 14
The Cellular Reprogramming Frontier
October 2026
Pulsed Yamanaka Factors, Epigenetic Clocks & The Reversal of Tissue Senescence
View Table of Contents
VOL. 13
Atomic AI & De Novo Protein Design
July 2026
From Zero-Shot Generative Enzymes to Sub-Angstrom Allosteric Prediction
View Table of Contents
VOL. 12
The Synthetic Organoid Era
April 2026
Multi-Lineage Micro-Tissues, Vascularized In Vitro Assays & Organ-on-Chip
View Table of Contents
VOL. 11
Neurotech & Synthetic Brains
January 2026
Optogenetic Neuromodulation, Synaptic Interfaces & Biological Computing
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